| 12/12/2019 |
| Porto - Feyenoord | 3-2 |
| Partizan Belgrade - Astana | 4-1 |
| Manchester United - AZ Alkmaar | 4-0 |
| Wolverhampton - Besiktas | 4-0 |
| Slovan Bratislava - Braga | 2-4 |
| Mönchengladbach - Istanbul Basaksehir | 1-2 |
| Roma - Wolfsberger AC | 2-2 |
| Ghent - FC Olexandria | 2-1 |
| Wolfsburg - Saint-Étienne | 1-0 |
| Espanyol Barcelona - CSKA Moscow | 0-1 |
| Ludogorets - Ferencvaros | 1-1 |
| Glasgow Rangers - Young Boys Bern | 1-1 |
| Apoel Nicosia - Sevilla | 1-0 |
| Qarabag - F91 Dudelange | 1-1 |
| Copenhagen - Malmö | 0-1 |
| Dynamo Kiev - Lugano | 1-1 |
| Getafe - Krasnodar | 3-0 |
| Basel - Trabzonspor | 2-0 |
| PSV - Rosenborg | 1-1 |
| LASK Linz - Sporting Portugal | 3-0 |
| Rennes - Lazio | 2-0 |
| Cluj - Celtic Glasgow | 2-0 |
| Standard - Arsenal | 2-2 |
| Frankfurt - Guimarães | 2-3 |
