Fixture list
| Preliminary round 1 2nd leg |
|---|
| 05/07/2016 | Birkirkara  | - |  Široki Brijeg | 2‑0 |
| 05/07/2016 | Chikhura  | - |  Zimbru | 2‑3 |
| 05/07/2016 | AS Jeunesse Esch  | - |  St. Patrick's Athletic | 2‑1 |
| 06/07/2016 | Infonet Tallinn  | - |  Heart of Midlothian | 2‑4 |
| 07/07/2016 | Ordabasy Shymkent  | - |  Cukaricki | 3‑3 |
| 07/07/2016 | Shirak  | - |  Dila Gori | 1‑0 |
| 07/07/2016 | Kairat  | - |  Teuta Durres | 5‑0 |
| 07/07/2016 | Pyunik  | - |  Europa FC | 2‑1 |
| 07/07/2016 | Dacia Chisinau  | - |  FC Kapaz | 0‑1 |
| 07/07/2016 | Spartak Myjava  | - |  Admira Mödling | 2‑3 |
| 07/07/2016 | Samtredia  | - |  FK Qabala | 2‑1 |
| 07/07/2016 | Rudar Pljevlja  | - |  Kukesi | 0‑1 |
| 07/07/2016 | FK Jelgava  | - |  Breidablik | 2‑2 |
| 07/07/2016 | RoPS  | - |  Shamrock Rovers | 1‑1 |
| 07/07/2016 | HJK  | - |  Atlantas Klaipeda | 1‑1 |
| 07/07/2016 | NK Lokomotiva  | - |  UE Santa Coloma | 4‑1 |
| 07/07/2016 | Debrecen  | - |  La Fiorita Montegiardino | 2‑0 |
| 07/07/2016 | Nomme JK Kalju  | - |  Traku FK | 4‑1 |
| 07/07/2016 | FK Neftchi  | - |  Balzan FC | 1‑2 |
| 07/07/2016 | MTK Budapest  | - |  Aktobe | 2‑0 |
| 07/07/2016 | Zaglebie Lubin  | - |  Slavia Sofia | 3‑0 |
| 07/07/2016 | FK Spartaks  | - |  Dinamo Minsk | 0‑2 |
| 07/07/2016 | Mariehamn  | - |  Odds Ballklubb | 1‑1 |
| 07/07/2016 | Radnik Bijeljina  | - |  Beroe | 0‑2 |
| 07/07/2016 | CS Fola Esch  | - |  Aberdeen | 1‑0 |
| 07/07/2016 | Omonoia Nicosia  | - |  FC Banants | 4‑1 |
| 07/07/2016 | Brondby  | - |  Valur | 6‑0 |
| 07/07/2016 | Gorica  | - |  Maccabi Tel-Aviv | 0‑1 |
| 07/07/2016 | Beitar Jerusalem  | - |  Sloboda Tuzla | 1‑0 |
| 07/07/2016 | Stabæk  | - |  Connah's Quay | 0‑1 |
| 07/07/2016 | Slovan Bratislava  | - |  Partizani | 13:00 |
| 07/07/2016 | Buducnost Podgorica  | - |  Rabotnicki Skopje | 1‑0 |
| 07/07/2016 | Suduva  | - |  Midtjylland | 0‑1 |
| 07/07/2016 | HB Torshavn  | - |  Levadia Maardu | 0‑2 |
| 07/07/2016 | FC Zaria  | - |  Videoton | 2‑0 |
| 07/07/2016 | Bala Town  | - |  AIK | 0‑2 |
| 07/07/2016 | Shakhtyor Soligorsk  | - |  NSI Runavik | 5‑0 |
| 07/07/2016 | Sileks  | - |  Vaduz | 1‑2 |
| 07/07/2016 | Llandudno  | - |  Göteborg | 1‑2 |
| 07/07/2016 | Vojvodina  | - |  FK Bokelj | 5‑0 |
| 07/07/2016 | Vikingur  | - |  Ventspils | 0‑2 |
| 07/07/2016 | KS Krakow  | - |  Shkendija | 1‑2 |
| 07/07/2016 | Hibernians  | - |  Spartak Trnava | 0‑3 |
| 07/07/2016 | Folgore  | - |  AEK Larnaca | 1‑3 |
| 07/07/2016 | Lusitanos  | - |  Domzale | 1‑2 |
| 07/07/2016 | Cliftonville  | - |  FC Differdange 03 | 2‑0 |
| 07/07/2016 | Cork City  | - |  Linfield | 1‑1 |
| 07/07/2016 | Glenavon  | - |  KR Reykjavik | 0‑6 |
| Preliminary round 2 1st leg |
|---|
| 14/07/2016 | Shirak | - | Spartak Trnava | 1‑1 |
| 14/07/2016 | Kairat | - | Maccabi Tel-Aviv | 1‑1 |
| 14/07/2016 | Dinamo Minsk | - | St. Patrick's Athletic | 1‑1 |
| 14/07/2016 | FK Neftchi | - | Shkendija | 0‑0 |
| 14/07/2016 | RoPS | - | NK Lokomotiva | 1‑1 |
| 14/07/2016 | Levadia Maardu | - |  Slavia Prague | 3‑1 |
| 14/07/2016 | Midtjylland | - | Vaduz | 3‑0 |
| 14/07/2016 | Debrecen | - |  Torpedo Zhodino | 1‑2 |
| 14/07/2016 | Zimbru | - |  Osmanlispor | 2‑2 |
| 14/07/2016 | Admira Mödling | - | FC Kapaz | 1‑0 |
| 14/07/2016 | Haecken  | - | Cork City | 1‑1 |
| 14/07/2016 | AIK | - | Europa FC | 1‑0 |
| 14/07/2016 | Beitar Jerusalem | - | Omonoia Nicosia | 1‑0 |
| 14/07/2016 | SonderjyskE  | - |  Strømsgodset | 2‑1 |
| 14/07/2016 | Maccabi Haifa  | - | Nomme JK Kalju | 1‑1 |
| 14/07/2016 | Shakhtyor Soligorsk | - | Domzale | 1‑1 |
| 14/07/2016 | Beroe | - | HJK | 1‑1 |
| 14/07/2016 | PAS Giannina  | - | Odds Ballklubb | 3‑0 |
| 14/07/2016 | Vojvodina | - | Connah's Quay | 1‑0 |
| 14/07/2016 | Maribor  | - |  Levski Sofia | 0‑0 |
| 14/07/2016 | Genk  | - | Buducnost Podgorica | 2‑0 |
| 14/07/2016 | Iasi  | - |  Hajduk Split | 2‑2 |
| 14/07/2016 | Partizan Belgrade  | - | Zaglebie Lubin | 0‑0 |
| 14/07/2016 | Slovan Bratislava | - | FK Jelgava | 0‑0 |
| 14/07/2016 | MTK Budapest | - | FK Qabala | 1‑2 |
| 14/07/2016 | Videoton | - | Cukaricki | 2‑0 |
| 14/07/2016 | Birkirkara | - | Heart of Midlothian | 0‑0 |
| 14/07/2016 | Hibernian  | - | Brondby | 0‑1 |
| 14/07/2016 | Aberdeen | - | Ventspils | 3‑0 |
| 14/07/2016 | Cliftonville | - | AEK Larnaca | 2‑3 |
| 14/07/2016 | Piast Gliwice  | - | Göteborg | 0‑3 |
| 14/07/2016 | Austria Wien  | - | Kukesi | 1‑0 |
| 14/07/2016 | KR Reykjavik | - |  Grasshopper | 3‑3 |
| Preliminary round 2 2nd leg |
|---|
| 20/07/2016 | FC Kapaz | - | Admira Mödling | 0‑2 |
| 21/07/2016 | Ventspils | - | Aberdeen | 0‑1 |
| 21/07/2016 | FK Jelgava | - | Slovan Bratislava | 3‑0 |
| 21/07/2016 | Nomme JK Kalju | - | Maccabi Haifa | 1‑1 |
| 21/07/2016 | Torpedo Zhodino | - | Debrecen | 1‑0 |
| 21/07/2016 | HJK | - | Beroe | 1‑0 |
| 21/07/2016 | NK Lokomotiva | - | RoPS | 3‑0 |
| 21/07/2016 | Omonoia Nicosia | - | Beitar Jerusalem | 3‑2 |
| 21/07/2016 | Odds Ballklubb | - | PAS Giannina | 3‑1 |
| 21/07/2016 | Grasshopper | - | KR Reykjavik | 2‑1 |
| 21/07/2016 | Strømsgodset | - | SonderjyskE | 2‑2 |
| 21/07/2016 | Slavia Prague | - | Levadia Maardu | 2‑0 |
| 21/07/2016 | Maccabi Tel-Aviv | - | Kairat | 2‑1 |
| 21/07/2016 | Göteborg | - | Piast Gliwice | 0‑0 |
| 21/07/2016 | Europa FC | - | AIK | 0‑1 |
| 21/07/2016 | Levski Sofia | - | Maribor | 1‑1 |
| 21/07/2016 | AEK Larnaca | - | Cliftonville | 2‑0 |
| 21/07/2016 | Vaduz | - | Midtjylland | 2‑2 |
| 21/07/2016 | FK Qabala | - | MTK Budapest | 2‑0 |
| 21/07/2016 | Kukesi | - | Austria Wien | 1‑4 |
| 21/07/2016 | Connah's Quay | - | Vojvodina | 1‑2 |
| 21/07/2016 | Osmanlispor | - | Zimbru | 5‑0 |
| 21/07/2016 | Brondby | - | Hibernian | 0‑1 |
| 21/07/2016 | Shkendija | - | FK Neftchi | 1‑0 |
| 21/07/2016 | Spartak Trnava | - | Shirak | 2‑0 |
| 21/07/2016 | Hajduk Split | - | Iasi | 2‑1 |
| 21/07/2016 | Cukaricki | - | Videoton | 1‑1 |
| 21/07/2016 | Domzale | - | Shakhtyor Soligorsk | 2‑1 |
| 21/07/2016 | Buducnost Podgorica | - | Genk | 2‑0 |
| 21/07/2016 | Cork City | - | Haecken | 1‑0 |
| 21/07/2016 | St. Patrick's Athletic | - | Dinamo Minsk | 0‑1 |
| 21/07/2016 | Heart of Midlothian | - | Birkirkara | 1‑2 |
| 21/07/2016 | Zaglebie Lubin | - | Partizan Belgrade | 0‑0 |
| Preliminary round 3 1st leg |
|---|
| 28/07/2016 | AEK Larnaca | - |  Spartak Moscow | 1‑1 |
| 28/07/2016 | FC Olexandria  | - | Hajduk Split | 0‑3 |
| 28/07/2016 | Heracles  | - |  Arouca | 1‑1 |
| 28/07/2016 | NK Lokomotiva | - |  Vorskla | 0‑0 |
| 28/07/2016 | Austria Wien | - | Spartak Trnava | 0‑1 |
| 28/07/2016 | Zaglebie Lubin | - | SonderjyskE | 1‑2 |
| 28/07/2016 | Slavia Prague | - |  Rio Ave | 0‑0 |
| 28/07/2016 | Göteborg | - | HJK | 1‑2 |
| 28/07/2016 | Torpedo Zhodino | - |  Rapid Wien | 0‑0 |
| 28/07/2016 | Lille  | - | FK Qabala | 1‑1 |
| 28/07/2016 | FK Jelgava | - | Beitar Jerusalem | 1‑1 |
| 28/07/2016 | Istanbul Basaksehir  | - |  Rijeka | 0‑0 |
| 28/07/2016 | Birkirkara | - |  Krasnodar | 0‑3 |
| 28/07/2016 | Luzern  | - |  Sassuolo | 1‑1 |
| 28/07/2016 | Grasshopper | - |  Apollon Limassol | 2‑1 |
| 28/07/2016 | Shkendija | - |  Mladá Boleslav | 2‑0 |
| 28/07/2016 | Panathinaikos  | - | AIK | 1‑0 |
| 28/07/2016 | Pandurii  | - | Maccabi Tel-Aviv | 1‑3 |
| 28/07/2016 | Vojvodina | - | Dinamo Minsk | 1‑1 |
| 28/07/2016 | Osmanlispor | - | Nomme JK Kalju | 1‑0 |
| 28/07/2016 | Genk | - | Cork City | 1‑0 |
| 28/07/2016 | Hertha Berlin  | - | Brondby | 1‑0 |
| 28/07/2016 | Videoton | - | Midtjylland | 0‑1 |
| 28/07/2016 | Ghent  | - |  Farul Constanța | 5‑0 |
| 28/07/2016 | Domzale | - |  West Ham | 2‑1 |
| 28/07/2016 | Aberdeen | - | Maribor | 1‑1 |
| 28/07/2016 | AZ Alkmaar  | - | PAS Giannina | 1‑0 |
| 28/07/2016 | Saint-Étienne  | - |  AEK Athens | 0‑0 |
| 28/07/2016 | Admira Mödling | - |  Slovan Liberec | 1‑2 |
| Preliminary round 3 2nd leg |
|---|
| 03/08/2016 | Slovan Liberec | - | Admira Mödling | 2‑0 |
| 04/08/2016 | Nomme JK Kalju | - | Osmanlispor | 0‑2 |
| 04/08/2016 | HJK | - | Göteborg | 0‑2 |
| 04/08/2016 | Midtjylland | - | Videoton | 1‑1 |
| 04/08/2016 | Spartak Moscow | - | AEK Larnaca | 0‑1 |
| 04/08/2016 | Spartak Trnava | - | Austria Wien | 0‑1 |
| 04/08/2016 | Krasnodar | - | Birkirkara | 3‑1 |
| 04/08/2016 | Vorskla | - | NK Lokomotiva | 2‑3 |
| 04/08/2016 | Beitar Jerusalem | - | FK Jelgava | 3‑0 |
| 04/08/2016 | Mladá Boleslav | - | Shkendija | 1‑0 |
| 04/08/2016 | Apollon Limassol | - | Grasshopper | 3‑3 |
| 04/08/2016 | PAS Giannina | - | AZ Alkmaar | 1‑2 |
| 04/08/2016 | FK Qabala | - | Lille | 1‑0 |
| 04/08/2016 | Arouca | - | Heracles | 0‑0 |
| 04/08/2016 | AIK | - | Panathinaikos | 0‑2 |
| 04/08/2016 | SonderjyskE | - | Zaglebie Lubin | 1‑1 |
| 04/08/2016 | Maccabi Tel-Aviv | - | Pandurii | 2‑1 |
| 04/08/2016 | Dinamo Minsk | - | Vojvodina | 0‑2 |
| 04/08/2016 | AEK Athens | - | Saint-Étienne | 0‑1 |
| 04/08/2016 | Brondby | - | Hertha Berlin | 3‑1 |
| 04/08/2016 | Farul Constanța | - | Ghent | 0‑0 |
| 04/08/2016 | Maribor | - | Aberdeen | 1‑0 |
| 04/08/2016 | Rijeka | - | Istanbul Basaksehir | 2‑2 |
| 04/08/2016 | Hajduk Split | - | FC Olexandria | 3‑1 |
| 04/08/2016 | Sassuolo | - | Luzern | 3‑0 |
| 04/08/2016 | Cork City | - | Genk | 1‑2 |
| 04/08/2016 | West Ham | - | Domzale | 3‑0 |
| 04/08/2016 | Rio Ave | - | Slavia Prague | 1‑1 |
| 04/08/2016 | Rapid Wien | - | Torpedo Zhodino | 3‑0 |
| Final preliminary round 1st leg |
|---|
| 17/08/2016 | Beitar Jerusalem | - | Saint-Étienne | 1‑2 |
| 18/08/2016 | Astana  | - |  Bate Borisov | 2‑0 |
| 18/08/2016 | Dinamo Tbilisi  | - |  PAOK Thessaloniki FC | 0‑3 |
| 18/08/2016 | SonderjyskE | - |  Sparta Prague | 0‑0 |
| 18/08/2016 | Midtjylland | - | Osmanlispor | 0‑1 |
| 18/08/2016 | Krasnodar | - | Partizani | 4‑0 |
| 18/08/2016 | AEK Larnaca | - | Slovan Liberec | 0‑1 |
| 18/08/2016 | Austria Wien | - |  Rosenborg | 2‑1 |
| 18/08/2016 | Slavia Prague | - |  Anderlecht | 0‑3 |
| 18/08/2016 | Göteborg | - |  Qarabag | 1‑0 |
| 18/08/2016 | Maccabi Tel-Aviv | - | Hajduk Split | 2‑1 |
| 18/08/2016 | FK Qabala | - | Maribor | 3‑1 |
| 18/08/2016 | Istanbul Basaksehir | - |  Shakhtyor Donetsk | 1‑2 |
| 18/08/2016 | NK Lokomotiva | - | Genk | 2‑2 |
| 18/08/2016 | Vojvodina | - | AZ Alkmaar | 0‑3 |
| 18/08/2016 | Fenerbahce  | - | Grasshopper | 3‑0 |
| 18/08/2016 | Panathinaikos | - | Brondby | 3‑0 |
| 18/08/2016 | Astra Ploiesti  | - | West Ham | 1‑1 |
| 18/08/2016 | Ghent | - | Shkendija | 2‑1 |
| 18/08/2016 | Sassuolo | - |  Red Star Belgrade | 3‑0 |
| 18/08/2016 | Arouca | - |  Olympiakos | 0‑1 |
| 18/08/2016 | Trencin  | - | Rapid Wien | 0‑4 |
| Final preliminary round 2nd leg |
|---|
| 25/08/2016 | Qarabag | - | Göteborg | 3‑0 |
| 25/08/2016 | Brondby | - | Panathinaikos | 1‑1 |
| 25/08/2016 | Slovan Liberec | - | AEK Larnaca | 3‑0 |
| 25/08/2016 | Rosenborg | - | Austria Wien | 1‑2 |
| 25/08/2016 | Grasshopper | - | Fenerbahce | 0‑2 |
| 25/08/2016 | Partizani | - | Krasnodar | 0‑0 |
| 25/08/2016 | Bate Borisov | - | Astana | 2‑2 |
| 25/08/2016 | PAOK Thessaloniki FC | - | Dinamo Tbilisi | 2‑0 |
| 25/08/2016 | Osmanlispor | - | Midtjylland | 2‑0 |
| 25/08/2016 | Genk | - | NK Lokomotiva | 2‑0 |
| 25/08/2016 | AZ Alkmaar | - | Vojvodina | 0‑0 |
| 25/08/2016 | Shkendija | - | Ghent | 0‑4 |
| 25/08/2016 | Anderlecht | - | Slavia Prague | 3‑0 |
| 25/08/2016 | Sparta Prague | - | SonderjyskE | 3‑2 |
| 25/08/2016 | Maribor | - | FK Qabala | 1‑0 |
| 25/08/2016 | Hajduk Split | - | Maccabi Tel-Aviv | 2‑1 |
| 25/08/2016 | Red Star Belgrade | - | Sassuolo | 1‑1 |
| 25/08/2016 | Olympiakos | - | Arouca | 2‑1 |
| 25/08/2016 | Saint-Étienne | - | Beitar Jerusalem | 0‑0 |
| 25/08/2016 | West Ham | - | Astra Ploiesti | 0‑1 |
| 25/08/2016 | Shakhtyor Donetsk | - | Istanbul Basaksehir | 2‑0 |
| 25/08/2016 | Rapid Wien | - | Trencin | 0‑2 |
| Matchday 1 - Group stage |
|---|
| 15/09/2016 | Qarabag | - | Slovan Liberec | 2‑2 |
| 15/09/2016 | Feyenoord  | - |  Manchester United | 1‑0 |
| 15/09/2016 | Zorya  | - | Fenerbahce | 1‑1 |
| 15/09/2016 | AZ Alkmaar | - |  Dundalk | 1‑1 |
| 15/09/2016 | Maccabi Tel-Aviv | - |  Zenit St. Petersburg | 3‑4 |
| 15/09/2016 | Young Boys Bern  | - | Olympiakos | 0‑1 |
| 15/09/2016 | Apoel Nicosia  | - | Astana | 2‑1 |
| 15/09/2016 | Viktoria Plzen  | - |  Roma | 1‑1 |
| 15/09/2016 | Astra Ploiesti | - | Austria Wien | 2‑3 |
| 15/09/2016 | Mainz  | - | Saint-Étienne | 1‑1 |
| 15/09/2016 | Anderlecht | - | FK Qabala | 3‑1 |
| 15/09/2016 | Rapid Wien | - | Genk | 3‑2 |
| 15/09/2016 | Sassuolo | - |  Bilbao | 3‑0 |
| 15/09/2016 | PAOK Thessaloniki FC | - |  Fiorentina | 0‑0 |
| 15/09/2016 | Red Bull Salzburg  | - | Krasnodar | 0‑1 |
| 15/09/2016 | Nice  | - |  Schalke | 0‑1 |
| 15/09/2016 | Internazionale  | - |  Hapoel Be'er Sheva | 0‑2 |
| 15/09/2016 | Southampton  | - | Sparta Prague | 3‑0 |
| 15/09/2016 | Konyaspor  | - | Shakhtyor Donetsk | 0‑1 |
| 15/09/2016 | Braga  | - | Ghent | 1‑1 |
| 15/09/2016 | Osmanlispor | - |  Steaua Bucharest | 2‑0 |
| 15/09/2016 | Villarreal  | - |  Zurich | 2‑1 |
| 15/09/2016 | Standard  | - |  Celta Vigo | 1‑1 |
| 15/09/2016 | Panathinaikos | - |  Ajax | 1‑2 |
| Matchday 2 - Group stage |
|---|
| 29/09/2016 | Astana | - | Young Boys Bern | 0‑0 |
| 29/09/2016 | FK Qabala | - | Mainz | 2‑3 |
| 29/09/2016 | Fiorentina | - | Qarabag | 5‑1 |
| 29/09/2016 | Slovan Liberec | - | PAOK Thessaloniki FC | 1‑2 |
| 29/09/2016 | Schalke | - | Red Bull Salzburg | 3‑1 |
| 29/09/2016 | Krasnodar | - | Nice | 5‑2 |
| 29/09/2016 | Sparta Prague | - | Internazionale | 3‑1 |
| 29/09/2016 | Hapoel Be'er Sheva | - | Southampton | 0‑0 |
| 29/09/2016 | Ghent | - | Konyaspor | 2‑0 |
| 29/09/2016 | Shakhtyor Donetsk | - | Braga | 2‑0 |
| 29/09/2016 | Zurich | - | Osmanlispor | 2‑1 |
| 29/09/2016 | Steaua Bucharest | - | Villarreal | 1‑1 |
| 29/09/2016 | Ajax | - | Standard | 1‑0 |
| 29/09/2016 | Celta Vigo | - | Panathinaikos | 2‑0 |
| 29/09/2016 | Fenerbahce | - | Feyenoord | 1‑0 |
| 29/09/2016 | Manchester United | - | Zorya | 1‑0 |
| 29/09/2016 | Zenit St. Petersburg | - | AZ Alkmaar | 5‑0 |
| 29/09/2016 | Dundalk | - | Maccabi Tel-Aviv | 1‑0 |
| 29/09/2016 | Olympiakos | - | Apoel Nicosia | 0‑1 |
| 29/09/2016 | Austria Wien | - | Viktoria Plzen | 0‑0 |
| 29/09/2016 | Roma | - | Astra Ploiesti | 4‑0 |
| 29/09/2016 | Saint-Étienne | - | Anderlecht | 1‑1 |
| 29/09/2016 | Bilbao | - | Rapid Wien | 1‑0 |
| 29/09/2016 | Genk | - | Sassuolo | 3‑1 |
| Matchday 3 - Group stage |
|---|
| 20/10/2016 | Slovan Liberec | - | Fiorentina | 1‑3 |
| 20/10/2016 | Qarabag | - | PAOK Thessaloniki FC | 2‑0 |
| 20/10/2016 | Krasnodar | - | Schalke | 0‑1 |
| 20/10/2016 | Red Bull Salzburg | - | Nice | 0‑1 |
| 20/10/2016 | Hapoel Be'er Sheva | - | Sparta Prague | 0‑1 |
| 20/10/2016 | Internazionale | - | Southampton | 1‑0 |
| 20/10/2016 | Shakhtyor Donetsk | - | Ghent | 5‑0 |
| 20/10/2016 | Konyaspor | - | Braga | 1‑1 |
| 20/10/2016 | Steaua Bucharest | - | Zurich | 1‑1 |
| 20/10/2016 | Osmanlispor | - | Villarreal | 2‑2 |
| 20/10/2016 | Celta Vigo | - | Ajax | 2‑2 |
| 20/10/2016 | Standard | - | Panathinaikos | 2‑2 |
| 20/10/2016 | Manchester United | - | Fenerbahce | 4‑1 |
| 20/10/2016 | Feyenoord | - | Zorya | 1‑0 |
| 20/10/2016 | Dundalk | - | Zenit St. Petersburg | 1‑2 |
| 20/10/2016 | AZ Alkmaar | - | Maccabi Tel-Aviv | 1‑2 |
| 20/10/2016 | Olympiakos | - | Astana | 4‑1 |
| 20/10/2016 | Young Boys Bern | - | Apoel Nicosia | 3‑1 |
| 20/10/2016 | Roma | - | Austria Wien | 3‑3 |
| 20/10/2016 | Viktoria Plzen | - | Astra Ploiesti | 1‑2 |
| 20/10/2016 | Saint-Étienne | - | FK Qabala | 1‑0 |
| 20/10/2016 | Mainz | - | Anderlecht | 1‑1 |
| 20/10/2016 | Genk | - | Bilbao | 2‑0 |
| 20/10/2016 | Rapid Wien | - | Sassuolo | 1‑1 |
| Matchday 4 - Group stage |
|---|
| 03/11/2016 | Astana | - | Olympiakos | 1‑1 |
| 03/11/2016 | Fenerbahce | - | Manchester United | 2‑1 |
| 03/11/2016 | Zorya | - | Feyenoord | 1‑1 |
| 03/11/2016 | Zenit St. Petersburg | - | Dundalk | 2‑1 |
| 03/11/2016 | Maccabi Tel-Aviv | - | AZ Alkmaar | 0‑0 |
| 03/11/2016 | Apoel Nicosia | - | Young Boys Bern | 1‑0 |
| 03/11/2016 | Austria Wien | - | Roma | 2‑4 |
| 03/11/2016 | Astra Ploiesti | - | Viktoria Plzen | 1‑1 |
| 03/11/2016 | FK Qabala | - | Saint-Étienne | 1‑2 |
| 03/11/2016 | Anderlecht | - | Mainz | 6‑1 |
| 03/11/2016 | Bilbao | - | Genk | 5‑3 |
| 03/11/2016 | Sassuolo | - | Rapid Wien | 2‑2 |
| 03/11/2016 | Fiorentina | - | Slovan Liberec | 3‑0 |
| 03/11/2016 | PAOK Thessaloniki FC | - | Qarabag | 0‑1 |
| 03/11/2016 | Schalke | - | Krasnodar | 2‑0 |
| 03/11/2016 | Nice | - | Red Bull Salzburg | 0‑2 |
| 03/11/2016 | Sparta Prague | - | Hapoel Be'er Sheva | 2‑0 |
| 03/11/2016 | Southampton | - | Internazionale | 2‑1 |
| 03/11/2016 | Ghent | - | Shakhtyor Donetsk | 3‑5 |
| 03/11/2016 | Braga | - | Konyaspor | 3‑1 |
| 03/11/2016 | Zurich | - | Steaua Bucharest | 0‑0 |
| 03/11/2016 | Villarreal | - | Osmanlispor | 1‑2 |
| 03/11/2016 | Ajax | - | Celta Vigo | 3‑2 |
| 03/11/2016 | Panathinaikos | - | Standard | 0‑3 |
| Matchday 5 - Group stage |
|---|
| 24/11/2016 | Fenerbahce | - | Zorya | 2‑0 |
| 24/11/2016 | Zenit St. Petersburg | - | Maccabi Tel-Aviv | 2‑0 |
| 24/11/2016 | Astana | - | Apoel Nicosia | 2‑1 |
| 24/11/2016 | FK Qabala | - | Anderlecht | 1‑3 |
| 24/11/2016 | Slovan Liberec | - | Qarabag | 3‑0 |
| 24/11/2016 | Fiorentina | - | PAOK Thessaloniki FC | 2‑3 |
| 24/11/2016 | Krasnodar | - | Red Bull Salzburg | 1‑1 |
| 24/11/2016 | Schalke | - | Nice | 2‑0 |
| 24/11/2016 | Hapoel Be'er Sheva | - | Internazionale | 3‑2 |
| 24/11/2016 | Sparta Prague | - | Southampton | 1‑0 |
| 24/11/2016 | Shakhtyor Donetsk | - | Konyaspor | 4‑0 |
| 24/11/2016 | Ghent | - | Braga | 2‑2 |
| 24/11/2016 | Steaua Bucharest | - | Osmanlispor | 2‑1 |
| 24/11/2016 | Zurich | - | Villarreal | 1‑1 |
| 24/11/2016 | Celta Vigo | - | Standard | 1‑1 |
| 24/11/2016 | Ajax | - | Panathinaikos | 2‑0 |
| 24/11/2016 | Manchester United | - | Feyenoord | 4‑0 |
| 24/11/2016 | Dundalk | - | AZ Alkmaar | 0‑1 |
| 24/11/2016 | Olympiakos | - | Young Boys Bern | 1‑1 |
| 24/11/2016 | Roma | - | Viktoria Plzen | 4‑1 |
| 24/11/2016 | Austria Wien | - | Astra Ploiesti | 1‑2 |
| 24/11/2016 | Saint-Étienne | - | Mainz | 0‑0 |
| 24/11/2016 | Genk | - | Rapid Wien | 1‑0 |
| 24/11/2016 | Bilbao | - | Sassuolo | 3‑2 |
| Matchday 6 - Group stage |
|---|
| 08/12/2016 | Qarabag | - | Fiorentina | 1‑2 |
| 08/12/2016 | PAOK Thessaloniki FC | - | Slovan Liberec | 2‑0 |
| 08/12/2016 | Konyaspor | - | Ghent | 0‑1 |
| 08/12/2016 | Braga | - | Shakhtyor Donetsk | 2‑4 |
| 08/12/2016 | Osmanlispor | - | Zurich | 2‑0 |
| 08/12/2016 | Villarreal | - | Steaua Bucharest | 2‑1 |
| 08/12/2016 | Rapid Wien | - | Bilbao | 1‑1 |
| 08/12/2016 | Feyenoord | - | Fenerbahce | 0‑1 |
| 08/12/2016 | Zorya | - | Manchester United | 0‑2 |
| 08/12/2016 | AZ Alkmaar | - | Zenit St. Petersburg | 3‑2 |
| 08/12/2016 | Maccabi Tel-Aviv | - | Dundalk | 2‑1 |
| 08/12/2016 | Young Boys Bern | - | Astana | 3‑0 |
| 08/12/2016 | Apoel Nicosia | - | Olympiakos | 2‑0 |
| 08/12/2016 | Viktoria Plzen | - | Austria Wien | 3‑2 |
| 08/12/2016 | Astra Ploiesti | - | Roma | 0‑0 |
| 08/12/2016 | Mainz | - | FK Qabala | 2‑0 |
| 08/12/2016 | Anderlecht | - | Saint-Étienne | 2‑3 |
| 08/12/2016 | Red Bull Salzburg | - | Schalke | 2‑0 |
| 08/12/2016 | Nice | - | Krasnodar | 2‑1 |
| 08/12/2016 | Internazionale | - | Sparta Prague | 2‑1 |
| 08/12/2016 | Southampton | - | Hapoel Be'er Sheva | 1‑1 |
| 08/12/2016 | Standard | - | Ajax | 1‑1 |
| 08/12/2016 | Panathinaikos | - | Celta Vigo | 0‑2 |
| 09/12/2016 | Sassuolo | - | Genk | 0‑2 |
| Round of 32 1st leg |
|---|
| 16/02/2017 | Krasnodar | - | Fenerbahce | 1‑0 |
| 16/02/2017 | Astra Ploiesti | - | Genk | 2‑2 |
| 16/02/2017 | AZ Alkmaar | - |  Lyon | 1‑4 |
| 16/02/2017 | Mönchengladbach  | - | Fiorentina | 0‑1 |
| 16/02/2017 | Celta Vigo | - | Shakhtyor Donetsk | 0‑1 |
| 16/02/2017 | Ghent | - |  Tottenham | 1‑0 |
| 16/02/2017 | Ludogorets  | - |  Copenhagen | 1‑2 |
| 16/02/2017 | Olympiakos | - | Osmanlispor | 0‑0 |
| 16/02/2017 | Rostov  | - | Sparta Prague | 4‑0 |
| 16/02/2017 | Anderlecht | - | Zenit St. Petersburg | 2‑0 |
| 16/02/2017 | Bilbao | - | Apoel Nicosia | 3‑2 |
| 16/02/2017 | Hapoel Be'er Sheva | - |  Besiktas | 1‑3 |
| 16/02/2017 | Legia Warsaw  | - | Ajax | 0‑0 |
| 16/02/2017 | Manchester United | - | Saint-Étienne | 3‑0 |
| 16/02/2017 | PAOK Thessaloniki FC | - | Schalke | 0‑3 |
| 16/02/2017 | Villarreal | - | Roma | 0‑4 |
| Round of 32 2nd leg |
|---|
| 22/02/2017 | Fenerbahce | - | Krasnodar | 1‑1 |
| 22/02/2017 | Saint-Étienne | - | Manchester United | 0‑1 |
| 22/02/2017 | Schalke | - | PAOK Thessaloniki FC | 1‑1 |
| 23/02/2017 | Osmanlispor | - | Olympiakos | 0‑3 |
| 23/02/2017 | Zenit St. Petersburg | - | Anderlecht | 3‑1 |
| 23/02/2017 | Apoel Nicosia | - | Bilbao | 2‑0 |
| 23/02/2017 | Besiktas | - | Hapoel Be'er Sheva | 2‑1 |
| 23/02/2017 | Ajax | - | Legia Warsaw | 1‑0 |
| 23/02/2017 | Roma | - | Villarreal | 0‑1 |
| 23/02/2017 | Genk | - | Astra Ploiesti | 1‑0 |
| 23/02/2017 | Lyon | - | AZ Alkmaar | 7‑1 |
| 23/02/2017 | Fiorentina | - | Mönchengladbach | 2‑4 |
| 23/02/2017 | Shakhtyor Donetsk | - | Celta Vigo | 0‑2 (a.e.t.) |
| 23/02/2017 | Tottenham | - | Ghent | 2‑2 |
| 23/02/2017 | Copenhagen | - | Ludogorets | 0‑0 |
| 23/02/2017 | Sparta Prague | - | Rostov | 1‑1 |
| Round of 16 1st leg |
|---|
| 09/03/2017 | Apoel Nicosia | - | Anderlecht | 0‑1 |
| 09/03/2017 | Rostov | - | Manchester United | 1‑1 |
| 09/03/2017 | Copenhagen | - | Ajax | 2‑1 |
| 09/03/2017 | Celta Vigo | - | Krasnodar | 2‑1 |
| 09/03/2017 | Schalke | - | Mönchengladbach | 1‑1 |
| 09/03/2017 | Lyon | - | Roma | 4‑2 |
| 09/03/2017 | Olympiakos | - | Besiktas | 1‑1 |
| 09/03/2017 | Ghent | - | Genk | 2‑5 |
| Round of 16 2nd leg |
|---|
| 16/03/2017 | Krasnodar | - | Celta Vigo | 0‑2 |
| 16/03/2017 | Besiktas | - | Olympiakos | 4‑1 |
| 16/03/2017 | Genk | - | Ghent | 1‑1 |
| 16/03/2017 | Anderlecht | - | Apoel Nicosia | 1‑0 |
| 16/03/2017 | Mönchengladbach | - | Schalke | 2‑2 |
| 16/03/2017 | Roma | - | Lyon | 2‑1 |
| 16/03/2017 | Manchester United | - | Rostov | 1‑0 |
| 16/03/2017 | Ajax | - | Copenhagen | 2‑0 |
| Quarter-final 1st leg |
|---|
| 13/04/2017 | Anderlecht | - | Manchester United | 1‑1 |
| 13/04/2017 | Celta Vigo | - | Genk | 3‑2 |
| 13/04/2017 | Ajax | - | Schalke | 2‑0 |
| 13/04/2017 | Lyon | - | Besiktas | 2‑1 |
| Quarter-final 2nd leg |
|---|
| 20/04/2017 | Manchester United | - | Anderlecht | 2‑1 (a.e.t.) |
| 20/04/2017 | Genk | - | Celta Vigo | 1‑1 |
| 20/04/2017 | Schalke | - | Ajax | 3‑2 (a.e.t.) |
| 20/04/2017 | Besiktas | - | Lyon | 2‑1 (a.e.t.) |
| Semi-final 1st leg |
|---|
| 03/05/2017 | Ajax | - | Lyon | 4‑1 |
| 04/05/2017 | Celta Vigo | - | Manchester United | 0‑1 |
| Semi-final 2nd leg |
|---|
| 11/05/2017 | Lyon | - | Ajax | 3‑1 |
| 11/05/2017 | Manchester United | - | Celta Vigo | 1‑1 |
| Final |
|---|
| 24/05/2017 | Ajax | - | Manchester United | 0‑2 |
